World journal of pharmaceutical research introduction silybum marianum l. Milk thistle medicinal uses to prevent cancer and protect against harmful effects of cancer therapy radiationinduced dermatitis is a common side effect of radiotherapy performed on cancer patients. Silybum marianum or milk thistle is an ancient curative herb, for its thorns also known as christs crown. Recently, a variety of liver diseases are spreading very rapidly in our society and different herbal remedies are used by the local practitioners as a therapeutic agent. Medicinal benefits and uses of milk thistle silybum marianum. Pdf a general introduction to medicinal plants and. Among these herbal formulations, silybum marianum is found to be highly effective. Silybin in neutral aqueous solutions has weak acidic properties, with a pka. Silymarin is an antioxidant that protects the liver from the free radical. Who monographs on selected medicinal plants volume 2. It also seems to have blood sugarlowering, antioxidant, and antiinflammatory effects. Milk thistle silybum marianum benefits, dosage and side effects.
Milk thistle silybum marianum 3 restorative medicine. Silybum marianum is native to a narrow area of the mediterranean, but has been naturalized throughout europe and along the chaparral coastal area of california in the united states. Silybum marianum is a plant that is used for centuries as a herbal treatment in liver and biliary tract diseases. The plant was originally used to help mothers produce milk purely because of the white leaf markings. Both silymarin and silybin inhibited free radicalinduced lipid peroxidation in microsomal and. Milk thistle silybum marianum is an annual or biennial plant of the asteraceae family. One study evaluated whether a milk thistle extract gel would help prevent radiodermatitis in people diagnosed with breast cancer. Milk thistle silybum marianum is an herbal supplement used to treat liver and biliary. Liver plant on the beautiful meadow in tara mountain, serbia milk thistle medical herb, silybum marianum, commonly cardus marianus wild plant with silimarin. Silybum marianum near the canal du rhone a sete in the. Milk thistle silybum marianum benefits, side effects. Flavonolignans are produced by the free radical oxidative coupling of the coniferyl. Milk thistle silybum marianum is a herbal product commonly used by patients with hiv for the management or prevention. Milk thistle is a dioecious, herbaceous plant that can be an annual or biennial depending on when the seed is sown.
Medicinal uses of ginger zingiber officinale roscoe improves growth and enhances immunity in aquaculture shubha ratna shakya abstract the medicinal plants are of great use in pharmaceutical, cosmetic, agricultural and food industry. Affordable and search from millions of royalty free images, photos and vectors. Silymarin is a natural compound derived from the species silybum marianum. Silybum marianum milk thistle description and constituents silybum marianum milk thistle has been used for centuries as an herbal medicine for the treatment of liver disease. Milk thistle is taken for its beneficial properties in treating hepatitis and liver cirrhosis. Its probably the most important herbal liver medicine out there and can be used very effectively to help limitprevent liver damage when exposed to toxinspoisons. Pdf medicinal properties of milk thistle with special reference to. Native to europe, the value of silybum marianum has been known for at least 2000 years as an important medicinal. Pdf use of plants based drugs for curing various ailments is as old as human civilization and is used in all cultures. The uses of silybum marianum as hepatoprotective dates back to 2000 years ago.
It originated in southern europe and was found all the way across to asia. Qualitative and quantitative composition 1, 2 wellestablished use. Such a use of medicinal plants plants are used for variety of purposes. Primary use of milk thistle is selftreatment of hepatic disorders most commonly treating hepatitis c. Dosages may range from 50 to 200 mg or more of silybum taken two or three times daily to support liver function, reduce cholesterol, and improve glycemic control. Milk thistle silybum marianum is an herbal supplement used. Flavolignans silymarin complex, flavonoids, volatile oil, bitter principle, mucilage actions.
Its probably the most important herbal liver medicine out there and can be used. No food use of milk thistle is given in kiple and ornelas 2000 although it has been used as a medicinal herb for thousands of years. The efficacy of some herbal products is beyond doubt, the most recent examples being silybum marianum linn. The extract of this herb is used to reap its cell regenerating benefits.
The use of medicinal plants in treating illnesses has been reported since ancestral times. Aster asteraceae hardy to zones 6 to 9, otherwise grown as a springplanted annual, 120 days to seed harvest annual or overwintering annual, native to the mediterranean and widely naturalized. The efficacy of some herbal products is beyond doubt, the most recent examples being silybum marianum. The silymarin, a mixture of three flavolignan isomers namely silybin 1, silydianin 2, and silychristin 3 is an active constituent of the plant. Milk thistle seed might protect liver cells from toxic chemicals and drugs. Medicinal properties of milk thistle with special reference. Thousands of new, highquality pictures added every day. Interactions with other medicinal products and other forms of interaction wellestablished use traditional use none reported.
Advances in the use of milk thistle silybum marianum janice. In india it is found commonly in jammu and kashmir. Its primary function is protecting the liver and treating liver and gallbladder problems. Silymarin acts as an antioxidant by reducing free radical production and lipid peroxidation. The young shoots in spring can be cut down to the root and boiled and buttered. This is how the nickname milk thistle came to life. Milk thistle seed silybum marianum side effects, facts. Silybum marianum milk thistle is currently utilised as a medicinal plant which provides raw material for the production of silymarin. Because silybum has been so widely studied, medicinal products and clinical studies are often standardized to approximately 80% silymarin content. It is an herbaceous plant and possesses certain specific medicinal properties and can also acts as a host for some pathogens.
Antiaflatoxin activities of milk thistle silybum marianum in broiler volume 73 issue 3 i. Jun 06, 2019 uses and health benefits of silybum marianum helps protect against cancer although more studies on mary thistles effects on cancer are still in early stages, it appears that this plant extract can have an inhibitory effect on the expansion of cancer cells and tumors on the skin and can also help prevent cancerous growth in the breast. Silybum marianum is a medicinal plant whose therapeutic. Milk thistle benefits milk thistle has been in use by herbalists for over 2,000 years in europe. Learn more about milk thistle uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain milk thistle. Article information, pdf download for advances in the use of milk thistle silybum marianum, open. Silybum marianum is used vigorously in cirrhosis, prostate, skin and breast cancer, cervical cells and kidney ailments. Milk thistle silybum marianum is a herbal product commonly used by patients with hiv for the management or prevention of antiretroviralinduced hepatotoxicity or liver disease caused by coinfection with hepatitis b or c 27. The young shoots in spring can be cut down to the root and. Pdf a general introduction to medicinal plants and silybum.
On the chemistry of silymarin silybin, the active principle of the fruits of silybum marianum. Silybum marianum originally comes from the mediterranean, although it is possible to grow it in. Milk thistle is a weed, which grows commonly in california and other parts of the world having a warm climate. Sep 01, 2015 silybum marianum, or more commonly referred to as milk thistle, is a native biennial plant. A general introduction to medicinal plants and silybum marianum. Silybum marianum urmia university of medical siences repository. Mar 27, 2014 the use of medicinal plants in treating illnesses has been reported since ancestral times. Hepatoprotective effect of silymarin pubmed central pmc. Silybum marianum is a familiar thorny plant thats prickly leaves contain splashes of white, which were historically referred to as mother marys milk.
Interactions with other medicinal products and other forms of interaction wellestablished use traditional use. Silybum marianum milk thistle and its main constituent. The milk thistle tablets i have seen actually come with a warning not to use if you are pregnant or breast feeding. It has also been shown to protect the liver against medications such as acetaminophen, a nonaspirin pain reliever. Milk thistle silybum marianum is a medicinal plant that has been. Research has shown that it promotes the regeneration of diseased liver cells and. Silymarin is claimed to be a free radical scavenger and to have hepatoprotectant properties. Milk thistle was approved in 1986 as a treatment for liver disease and it is widely used to treat alcoholic hepatitis, alcoholic fatty liver, cirrhosis, liver poisoning and viral hepatitis.
Milk thistle is an annual or biennial plant of the asteraceae family, native of souther europe through to asia. Read more about the prescription drug milk thistle silybum marianum. European union herbal monograph on silybum marianum l. Herb medical milk thistle stock photos download 676 royalty. Silybum marianum milk thistle, blessed milkthistle pfaf. Germany is the largest producer of milk thistle using it for dyspeptic complaints and various amounts of liver conditions. However, silybin containing 1, 4dioxane ring is the most potent antihepatotoxic agent. Uses described in pharmacopoeias and in traditional systems of medicine. A general introduction to medicinal plants and silybum marianum a. Milk thistle silybum marianum benefits, dosage and side. Apr 26, 2017 milk thistle, or silybum marianum, is a commonly used herbal medicine in the management of several disorders. Its scientific name is silybum marianum and can be found in natural products stores, manipulation pharmacies and some free.
Silybum marianum has been used to treat certain health problems, such as stomach, liver and gall bladder disorders etc. In the case of hepatic diseases, several species such as silybum marianum, phyllanthus niruri, and panus giganteus berk. Milk thistle has also been known to be used as food. Milk thistle silybum marianum is a herbal product commonly used by patients with hiv for the management or prevention of antiretroviralinduced hepatotoxicity or liver disease caused by co.
Effects of silybum marianum on patients with chronic. Milk thistle herb uses, side effects and health benefits. Uses and health benefits of silybum marianum helps protect against cancer although more studies on mary thistles effects on cancer are still in early stages, it appears that this plant. It has since then expanded and is now found all over the world. Molecular analysis of genetic diversity in population of. Its scientific name is silybum marianum and can be found in natural products stores, manipulation pharmacies and some free trade shows. Information on documented medicinal use and historical data from. Silybum marianum is sometimes known as blessed thistle. Advances in the use of milk thistle silybum marianum. Tahir skip to main content accessibility help we use. Blessed thistle has a long history of use in the west as a remedy for depression and liver problems. Silymarin is composed of a group of flavonolignans that are well known and studied for their medicinal properties. Consumer information about the medication milk thistle silybum marianum oral, includes side effects, drug interactions, recommended dosages, and storage information.
Name of the medicinal product to be specified for the individual finished product. Milk thistle, or silybum marianum, is a commonly used herbal medicine in the management of several disorders. Different plant parts have been used from the last 2000 years in the preparations of various traditional medicines. Silybum marianum, silymarin, hepatoprotective remedy, antioxidant received november 3, 2014. Silybum marianum milk thistle, blessed milkthistle pfaf plant. Silybum marianum is a medicinal plant used widely for treating liver diseases. Marian thistle, also known as milk thistle, cardosanto or leafstrap, is a medicinal plant widely used to make home remedies for problems in the liver and gallbladder, for example. Among these herbal formulations, silybum marianum is found to be highly effective for liver disorders. It can be used like extract or for tea milk thistle medical herb, silybum marianum, commonly cardus marianus wild plant with silimarin. Recent research has confirmed that it has a remarkable ability to protect the liver from damage resulting from alcoholic and other types of poisoning.
Effects of silybum marianum on patients with chronic hepatitis c hamid kalantari, a zahra shahshahan, b sayed mehdi hejazi, c taghi ghafghazi, d and vahid sebghatolahi e a. Thistle, milk silybum marianum seeds, organic wa no. Find silybum marianum stock images in hd and millions of other royalty free stock photos, illustrations and vectors in the shutterstock collection. This fairly typical thistle has red to purple flowers and shiny pale green leaves with white veins. Biochar application and drought stress effects on physiological characteristics of silybum marianum. The roots can be eaten raw or boiled and buttered or parboiled and roasted. Jan 06, 2011 effects of silybum marianum on patients with chronic hepatitis c hamid kalantari, a zahra shahshahan, b sayed mehdi hejazi, c taghi ghafghazi, d and vahid sebghatolahi e a associate professor of gastroenterology, school of medicine, isfahan university of medical sciences, isfahan, iran. Effects of silybum marianum on patients with chronic hepatitis c. The silymarin, a mixture of three flavolignan isomers namely silybin 1, silydianin 2, and silychristin 3 is an active constituent. The milk thistle silybum marianum and silymarin as. Silybum marianum or milk thistle mt is the most wellresearched plant in the treatment of liver disease.
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